BioPOLIM - Polarization resolved fluorescence microscopy

projects & grants
DFG logo

DFG project funding Ta 1049/2 Live Cell 2D polarization imaging (Live2DPOLIM) – an imaging technique for observation of nanoscale protein aggregation and molecular (re-)arrangements in live cells (June 2020 - May 2023) in the Microscopy Department of Rainer Heintzmann at the Leibniz Institute of Photonic Technology, Jena & Nanoimaging (Nanobiophotonics) Group at Friedrich-Schiller University, Jena.


Laserlab Europe logo LLC logo

Laserlab-Europe access grant LLC002451 in 2018 Investigation of apical f-actin aggregation in healthy and cholestatic liver tissue using 2D polarisation imaging to Lund Laser Center SMS group of Ivan Scheblykin together with Adrian Press, head of the Nanophysiology Group, Friedrich-Schiller-University Hospital Jena. Receiving funding from the European Union's Horizon 2020 research and innovation programme under grant agreement no 654148 Laserlab-Europe.


DFG logo

DFG personal research grant Ta 1049/1 2D polarisation resolved optical spectroscopy on macromolecules (conjugated polymers and proteins) in different environments for investigation of conformation, aggregation and energy transfer with the intention to improve organic solar cells (October 2014 - March 2016) in the Single molecule spectroscopy group of Ivan Scheblykin at Lunds Universitet, Sweden.

methods
areas of research
protein aggregation

BioImaging: Protein aggregation ex vivo visualized using 2D polarization imaging

  • A.T. Press, P. Babic, A. Medyukhina, A. Ramoji, B. Hoffmann, J. Benecke, W. Foo, M. Rodewald, A. Wiede, W. Hauswald, T. Mueller, J. Shi, D. Täuber, C. Karras, T. Meyer, Z.Cseresnyes, I. Nishang, S. Hoeppener, M.H. Gräler, R. Wetzker, I.G. Scheblykin, I. Rubio, R. Heintzmann, J. Popp, M.-T. Figge, U.S. Schubert. M. Bauer: submitted
  • D. Täuber, A.T. Press, P. Martinac, K.-J. Benecke, M. Bauer, J. Shi, R. Camacho, I.G. Scheblykin, Laserlab Europe User Meeting, November 2018. book of abstracts
  • R. Camacho, D. Täuber, C. Hansen, J. Shi, L. Bousset, R. Melki, J.-Y. Li, I.G. Scheblykin, Communications Biology, 1, 157, 2018. article
polymer films

2D polarization imaging of organic solar cell materials

  • R. Camacho, D. Täuber, I.G. Scheblykin, REVIEW: Fluorescence anisotropy reloaded – emerging polarization microscopy methods for assessing chromophores’ organization and excitation energy transfer in single molecules, particles, thin films and beyond. Advanced Materials, 31, 1805671, 2019. abstract
  • D. Täuber, W. Cai, O. Inganäs, I.G. Scheblykin, ACS Omega, 2(1), 32-40, 2017. ACS Live Slide Presentation, article
  • D. Täuber, Y. Tian, Y. Xia, O. Inganäs, I.G. Scheblykin, J. Phys. Chem. C, 121(40), 21848-21856, 2017. abstract
  • D. Täuber, W. Cai, Y. Xia, O Inganäs, I.G. Scheblykin, in: „Self-Assembly in the world of polymers, 80th Prague Meeting on Macromolecules,“ eds: P. Stepanek, J. Kotek, Institute of Macromolecular Chemistry of the Academy of Sciences of the Czech Republic, ISBN 978-80-85009-85-9, p. 85, 2016.
perovskite nano-objects

Photoluminescence polarization properties of (organo-)metal halide perovskite

  • M. Goldmann, J. Shi, J. Chen , M.E. Messing, K. Zheng, T. Pullerits, I.G. Scheblykin, D. Täuber, in preparation.
  • D. Täuber, A. Dobrovolsky, R. Camacho, I.G. Scheblykin, Nano Letters, 16(8), 5087–5094, 2016. abstract
thin_LC_films

Thin liquid crystal films

  • D. Täuber, K. Radscheit, C. von Borczyskowski, M. Schulz, and V. Al. Osipov, Phys. Rev. E, 94(1), 012804, 2016. abstract arXiv
  • D. Täuber, and C. von Borczyskowski, REVIEW: Single Molecule Studies on Dynamics in Liquid Crystals. Int. J. Mol. Sci., 14, 19506-19525, 2013. abstract & article
  • B. Schulz, D. Täuber, J. Schuster, T. Baumgärtel, and C. von Borczyskowski, Soft Matter, 7(16), 7431 - 7440, 2011. abstract open access by TU Chemnitz/DFG
  • B. Schulz, D. Täuber, F. Friedriszik, H. Graaf, J. Schuster and C. von Borczyskowski Phys. Chem. Chem. Phys., 12(37), 11555-11564, 2010. abstract

collaboration
Nanophysiology group Nanophysiology, Jena University Hospital, Germany
Center for Sepsis Control and Care Center for Sepsis Control & Care, Jena University Hospital, Germany
Lund SMS group Single Molecule Spectroscopy, Lund University, Sweden
linkoping biorgel group Biomolecular and Organic Electronics, Linköping University, Sweden
BMC - Neural Plasticity and Repair Neural Plasticity and Repair, BMC, Lund University, Sweden
eCOST MP1302 Nanospectroscopy e-COST Action MP1302 Nanospectroscopy
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